The ACG Procedure

The ACG Procedure, which has been developed by Sonovum AG and is based on proprietary patents, is a supplement and alternative method for high-radiation and cost-intensive procedures like MRI or CT.

Clinical Partners' Testimonials

In Permanent Monitoring on the ICU as well as before, during and after surgery settings, ACG can be used for monitoring brain tissue in real time. In a number of research cooperations, we are aiming at the CE sign for a IIb Medical Device (MDR).

Sonovum AG
PD Dr. Martin Sauer

"In a pilot trial about the diagnosis of septic encephalopathies (early septicemia syndrom), we researched how ACG can be used fot its identification. The preliminary results have been very promising which is why we are going ahead and planning the next step of this study setting. It will be multicentric and comprise more patients, more diagnosis methods as well as more elaborate testing methodolgy. For us, this area of pre-diagnosis and Permanent Monitoring shows a lot of further potential: with ACG, we want to be able to diagnose the septic encephalopathy while it evolves. During that period, we want to study its process in order to help patients earlier and more effectively than we traditionally can.“

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Areas of application

Extracts from relevant studies and publications

Dobkowska-Chudon et al.: "Detecting cerebrovascular changes in the brain caused by hypertension in atrial fibrillation group using acoustocerebrography", PLoS ONE 2018, Volume 13, Issue 7 

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Sauer et al.: "Diagnose einer septischen Enzephalopathie durch Akustocerebrografie - Ergebnisse einer Pilotstudie"; Poster presented at DIVI Leipzig, Dec 8, 2017; E-Poster Ref. No. EP/11/01

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Sievert et al.: "Pilotstudie zur Diagnose einer septischen Enzephalopathie durch Akustocerebrografie - Zwischenauswertung"; Poster presented at DAC Nuremberg, May 4, 2017; E-Poster Ref. No. 2.2.12

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Olszewski et al.: "The novel non-invasive ultrasound device for detecting early changes of the brain in patients with heart failure", European Journal of Heart Failure 2016, Volume 18, Issue Supplement S1

Abstracts as PDF

Bogdan et al.: Computer Aided Multispectral Ultrasound Diagnostics Brain Health Monitoring System based on Acoustocerebrography, Conference Paper submitted for MEDICO 2016, Cyprus

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Wrobel et al.: “On ultrasound classification of stroke risk factors from randomly chosen respondents using non-invasive multispectral ultrasonic brain measurements and adaptive profiles”, Biocybernetics and Biomedical Engineering 2015, Volume 35, Issue 4

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Come and make medical history with us

The procedure and range of options offered by this device are to a certain extent, unlimited. We have already explored some applications; many others have also been hypothesized.

The interpretation of the measurement results and its correlation with clinical data is an ongoing process. Cooperation with a variety of specialized doctors using the ACG device suggests that new medical findings can be discovered and explored.

Contact us and become a research partner!

Future Research Partners

Sonovum AG
Perlickstraße 5 | 04103 Leipzig

+49 341 39299-510

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Publisher responsible for contents of this website:

Sonovum AG
Perlickstraße 5
04103 Leipzig

Telephone: +49 341 39299-510

Sales tax identification number according to §27 German Sales Tax Law: DE281226472
Commercial Registered - Leipzig Court: HRB 27913

Responsible according to § 55 section 2 RStV and TMG: Bertram König

CEO: Bertram König
CTO: Miroslaw Wrobel
Chairman of the Supervisory Board: Bernd Minning


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